Siloxia, a versatile pharmaceutical silica platform

Siloxia is a pharmaceutical silica-based technology service platform that opens up many possibilities for an increased active pharmaceutical ingredient (API) and formulation performance. Mesoporous silica is a very versatile product that can be used in a large number of pharmaceutical applications such as active pharmaceutical ingredient carrier, SEDDS systems, suspensions, moisture protection, controlled release and process related parameters like tableting glidant and disintegration aid. It can be applied for both hydrophilic and hydrophobic API’s.

Especially in cases where the active pharmaceutical ingredient faces certain limitations like lipid nature, liquisolid, oil, polymorphic changes, limited solubility or instability, mesoporous silica can be a straight-forward solution to overcome these challenges.

Mesoporous silica consist of small particles containing predefined pores creating a very large surface area in which the active pharmaceutical ingredient can be absorbed. Solvent impregnation is a well-known technique to incorporate active pharmaceutical ingredient in silica pores, Siloxia also offers the possibility to load pores without the use of solvents by using a dry loading technology.